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Presented by Hind Nassar, M.D. and prepared by Alex Chang, M.D.
Case 2: Axillary sentinel lymph node biopsy in a 60 year old woman with invasive mammary carcinoma.
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Question 1 of 1
1. Question
Week 419: Case 2
Axillary sentinel lymph node biopsy in a 60 year old woman with invasive mammary carcinoma with ductal and lobular features.
Correct
Answer: Capsular nevus
Histology: none provided
Discussion: Nevus cells can be seen in axillary lymph nodes from women with breast cancer. They can be mistaken for metastatic breast carcinoma or metastatic melanoma. However the fact that they are confined to the capsule and have bland cytological features in addition of being positive for Melan-A and negative for HMB45 and cytokeratin on immunostain is helpful in the differential diagnosis.
Incorrect
Answer: Capsular nevus
Histology: none provided
Discussion: Nevus cells can be seen in axillary lymph nodes from women with breast cancer. They can be mistaken for metastatic breast carcinoma or metastatic melanoma. However the fact that they are confined to the capsule and have bland cytological features in addition of being positive for Melan-A and negative for HMB45 and cytokeratin on immunostain is helpful in the differential diagnosis.
