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Presented by Hind Nassar, M.D. and prepared by Aatur Singhi, M.D., Ph.D.
Case 5: Tongue mass in a 64 year old patient with history of squamous cell carcinoma of the tongue.
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1. Question
Week 414: Case 5
Tongue mass in a 64 year old patient with history of squamous cell carcinoma of the tongue treated with surgery and radiationimages/1alex/110209case5image1.jpg
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images/1alex/110209case5image5.jpgCorrect
Answer: Metastatic renal cell carcinoma to scar
Histology: none provided
Discussion: The lesion has clear cell features and is positive for PAX8 and CD10 and negative for p63, consistent with a metastatic renal cell carcinoma to the scar of previous surgery. It is a diagnosis to keep in mind in case of a clear cell tumor, especially that renal cell carcinoma can metastasize to various sites including other tumors.
Incorrect
Answer: Metastatic renal cell carcinoma to scar
Histology: none provided
Discussion: The lesion has clear cell features and is positive for PAX8 and CD10 and negative for p63, consistent with a metastatic renal cell carcinoma to the scar of previous surgery. It is a diagnosis to keep in mind in case of a clear cell tumor, especially that renal cell carcinoma can metastasize to various sites including other tumors.
