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Presented by Ralph Hruban, M.D. and prepared by Orin Buetens, M.D.
Case 4: This 48 year-old female had a needle biopsy of her breast for microcalcification which were discovered on routine mammography.
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1. Question
Week 39: Case 4
This 48 year-old female had a needle biopsy of her breast for microcalcification which were discovered on routine mammography./images/8411a.jpg
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/images/8411c.jpgCorrect
Answer: Sclerosing adenosis involving a nerve
Histology: By light microscopy, sclerosing adenosis is typically characterized by a lobulocentric growth pattern, deformed glandular elements, and the maintenance (focally) of a two-cell population
Discussion: Extension of the benign glands into perineural spaces has been reported to occur in approximately 2% of cases with sclerosing adenosis. These lesions should not be mistaken for evidence of an invasive cancer.
Incorrect
Answer: Sclerosing adenosis involving a nerve
Histology: By light microscopy, sclerosing adenosis is typically characterized by a lobulocentric growth pattern, deformed glandular elements, and the maintenance (focally) of a two-cell population
Discussion: Extension of the benign glands into perineural spaces has been reported to occur in approximately 2% of cases with sclerosing adenosis. These lesions should not be mistaken for evidence of an invasive cancer.
