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Presented by Ralph Hruban, M.D. and prepared by Shien Micchelli, M.D.
Case 5: This 12 year-old girl developed unilateral breast enlargement that extended in the axilla.
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1. Question
Week 288: Case 5
This 12 year-old girl developed unilateral breast enlargement that extended in the axilla.images/10_30_06_5a.jpg
images/10_30_06_5b.jpg
images/10_30_06_5c.jpgCorrect
Answer: Juvenile hypertrophy
Histology: The breast tissue resected from the axilla shows ducts with a prominent stroma, but no lobules.
Discussion: Juvenile hypertrophy occurs in 11 to 14 year-olds. In some cases, the growth of breast parenchyma can be dramatic. Microscopically, as in this case, juvenile hypertrophy has an almost gynecomastoid appearance with ducts without lobules surrounded by a prominent cellular stroma. This lesion is benign.
Incorrect
Answer: Juvenile hypertrophy
Histology: The breast tissue resected from the axilla shows ducts with a prominent stroma, but no lobules.
Discussion: Juvenile hypertrophy occurs in 11 to 14 year-olds. In some cases, the growth of breast parenchyma can be dramatic. Microscopically, as in this case, juvenile hypertrophy has an almost gynecomastoid appearance with ducts without lobules surrounded by a prominent cellular stroma. This lesion is benign.
