Quiz-summary
0 of 1 questions completed
Questions:
- 1
Information
Presented by Fred Askin, M.D. and prepared by Jeffrey T. Schowinsky, M.D.
Case 1: 18 year old girl with a left neck mass
You have already completed the quiz before. Hence you can not start it again.
Quiz is loading...
You must sign in or sign up to start the quiz.
You have to finish following quiz, to start this quiz:
Results
Time has elapsed
Categories
- Not categorized 0%
- 1
- Answered
- Review
-
Question 1 of 1
1. Question
Week 276: Case 1
18 year old girl with a left neck massimages/072406FA1a.jpg
images/072406FA1b.jpg
images/072406FA1c.jpg
images/072406FA1d.jpg
images/072406FA1e.jpgCorrect
Answer: Nodular lymphocyte-predominance Hodgkin lymphoma
Histology: This lesion is a nodular, polymorphous proliferation of scattered large neoplastic cells set in a background of non-neoplastic B-Lymphocytes. The large cells are Reed-Sternberg Cell variants known as “popcorn” or “L&H Cells” (lymphocytic and/or histiocytic R-S cell variants). The cells usually have one large nucleus and scant cytoplasm. The nuclei are often lobulated or folded and the cells are positive for B-cell markers. In general, variants lack CD15 and CD30 positivity.
Discussion: In areas with a more diffuse growth pattern, T-cells may be numerous and cause great difficulty in separating NLP Hodgkin from T-cell rich large B-cell lymphoma.
Reference(s):
– Jaffe ES, Harris NL, Stein H, and Vardiman JW. Tumors of Haematopoetic and Lymphoid Tissue. Lyon, IARC Press, 2001.Incorrect
Answer: Nodular lymphocyte-predominance Hodgkin lymphoma
Histology: This lesion is a nodular, polymorphous proliferation of scattered large neoplastic cells set in a background of non-neoplastic B-Lymphocytes. The large cells are Reed-Sternberg Cell variants known as “popcorn” or “L&H Cells” (lymphocytic and/or histiocytic R-S cell variants). The cells usually have one large nucleus and scant cytoplasm. The nuclei are often lobulated or folded and the cells are positive for B-cell markers. In general, variants lack CD15 and CD30 positivity.
Discussion: In areas with a more diffuse growth pattern, T-cells may be numerous and cause great difficulty in separating NLP Hodgkin from T-cell rich large B-cell lymphoma.
Reference(s):
– Jaffe ES, Harris NL, Stein H, and Vardiman JW. Tumors of Haematopoetic and Lymphoid Tissue. Lyon, IARC Press, 2001.
