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Presented by Ralph Hruban, M.D. and prepared by Amy Duffield, M.D., Ph.D.
Case 4: This 25 year-old woman had recurrent abdominal pain and CT revealed a large intra-abdominal mass that was not responsive to medical management.
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1. Question
Week 321: Case 4
This 25 year-old woman had recurrent abdominal pain and CT revealed a large intra-abdominal mass that was not responsive to medical management./images/4A_08_13_07.jpg
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/images/4D_08_13_07.jpgCorrect
Answer: Endometriosis
Histology: This dense fibrotic stroma is infiltrated by numerous small glands. The epithelial cells are uniform, and are surrounded by spindle-shaped cells and occasional hemosiderin-laden macrophages.
Discussion: Endometriosis, the presence of endometrial glands with associated stroma in an ectopic location, can be a real mimicker of metastatic carcinoma. Common locations for endometriosis include the ovaries, uterine ligaments, peritoneum, bladder and rectosigmoid.
Incorrect
Answer: Endometriosis
Histology: This dense fibrotic stroma is infiltrated by numerous small glands. The epithelial cells are uniform, and are surrounded by spindle-shaped cells and occasional hemosiderin-laden macrophages.
Discussion: Endometriosis, the presence of endometrial glands with associated stroma in an ectopic location, can be a real mimicker of metastatic carcinoma. Common locations for endometriosis include the ovaries, uterine ligaments, peritoneum, bladder and rectosigmoid.
