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Presented by Dr. Andres Matoso and prepared by Dr. Yembur Ahmad
This case talks about a 50 year old male with a testicular tumor.
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1. Question
A 50 year old male presents with a testicular tumor.
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Correct: D
Histology: This tumor is centered in the hilum of the testis and invades the epididymis and testicular parenchyma and is composed of large solid nests of tumor cells with central necrosis.
Discussion: Colon cancer usually metastasizes to regional lymph nodes, liver, lung, bone, and brain. Metastatic colorectal carcinoma to the testis is rare. In general, secondary malignancies of the testis are rare and the most common sites of origin include prostate, stomach, lung, malignant melanoma, pancreas and renal cell carcinoma. The key to arrive at the diagnosis is to recognize the absence of intratubular germ cell neoplasia in-situ in the surrounding testis and knowing the clinical history of previous malignancy. Most commonly, metastatic tumors are centered in the hilum of the testis in the junction of the testicular parenchyma and the epididymis.
References:
1. Hatoum HA, Abi Saad, GS, Otrock ZK, Barada KA, Shamseddine AI. Int J Clin Oncol (2011) 16:203-209Incorrect
Correct: D
Histology: This tumor is centered in the hilum of the testis and invades the epididymis and testicular parenchyma and is composed of large solid nests of tumor cells with central necrosis.
Discussion: Colon cancer usually metastasizes to regional lymph nodes, liver, lung, bone, and brain. Metastatic colorectal carcinoma to the testis is rare. In general, secondary malignancies of the testis are rare and the most common sites of origin include prostate, stomach, lung, malignant melanoma, pancreas and renal cell carcinoma. The key to arrive at the diagnosis is to recognize the absence of intratubular germ cell neoplasia in-situ in the surrounding testis and knowing the clinical history of previous malignancy. Most commonly, metastatic tumors are centered in the hilum of the testis in the junction of the testicular parenchyma and the epididymis.
References:
1. Hatoum HA, Abi Saad, GS, Otrock ZK, Barada KA, Shamseddine AI. Int J Clin Oncol (2011) 16:203-209
