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Presented by Dr. Elizabeth Thompson and prepared by Dr. Tatianna Larman.
A sinonasal mass in a 55 year old woman.
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Question 1 of 1
1. Question
A sinonasal mass in a 55 year old. Choose the correct diagnosis.
Correct
Answer: Adenoid cystic carcinoma
Histology: This tumor is comprised of a combination of patterns: cribriform, tubular and solid, formed primarily by dark, basaloid round-to-angulated cells. A second population of round cells with eosinophilic cytoplasm can also be appreciated, imparting a biphasic appearance to certain areas. Matrix material can be seen in some of the “punched out” spaces in the cribriform areas. Significant cellular pleomorphism and mitotic activity are not appreciated.
Discussion: This tumor is comprised of a combination of patterns: cribriform, tubular and solid, formed primarily by dark, basaloid round-to-angulated cells. A second population of round cells with eosinophilic cytoplasm can also be appreciated, imparting a biphasic appearance to certain areas. Matrix material can be seen in some of the “punched out” spaces in the cribriform areas. Significant cellular pleomorphism and mitotic activity are not appreciated.
Incorrect
Answer: Adenoid cystic carcinoma
Histology: This tumor is comprised of a combination of patterns: cribriform, tubular and solid, formed primarily by dark, basaloid round-to-angulated cells. A second population of round cells with eosinophilic cytoplasm can also be appreciated, imparting a biphasic appearance to certain areas. Matrix material can be seen in some of the “punched out” spaces in the cribriform areas. Significant cellular pleomorphism and mitotic activity are not appreciated.
Discussion: This tumor is comprised of a combination of patterns: cribriform, tubular and solid, formed primarily by dark, basaloid round-to-angulated cells. A second population of round cells with eosinophilic cytoplasm can also be appreciated, imparting a biphasic appearance to certain areas. Matrix material can be seen in some of the “punched out” spaces in the cribriform areas. Significant cellular pleomorphism and mitotic activity are not appreciated.
