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Presented by Ralph Hruban, M.D. and prepared by Lynette S. Nichols, M.D.
Case 6: This patient had a biopsy proven adenocarcinoma of the prostate.
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1. Question
Week 137: Case 6
This patient had a biopsy proven adenocarcinoma of the prostate. A radical prostatectomy with lymph node dissection was performed. The slide is from one of the lymph nodes./images/Lyn’s/h6a.jpg
/images/Lyn’s/h6b.jpg
/images/Lyn’s/h6c.jpgCorrect
Answer: Sinus histiocytosis after hip replacement
Histology: The sinuses of this node are distended with numerous pigment containing macrophages.
Discussion: Sinus histiocytosis of the pelvic lymph nodes owes in some patients following hip replacement. The lymph nodes often have a black-brown cut surface and microscopically numerous histiocytes containing dark microparticles. These microparticles are composed of cobalt-chromium and titanium.
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Answer: Sinus histiocytosis after hip replacement
Histology: The sinuses of this node are distended with numerous pigment containing macrophages.
Discussion: Sinus histiocytosis of the pelvic lymph nodes owes in some patients following hip replacement. The lymph nodes often have a black-brown cut surface and microscopically numerous histiocytes containing dark microparticles. These microparticles are composed of cobalt-chromium and titanium.
