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Presented by Jonathan Epstein, M.D. and prepared by Jospeh Kronz, M.D.
Case 2: 14-year-old male with nose bleed
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Question 1 of 1
1. Question
Week 2: Case 2
14-year-old male with nose bleed
Correct
Answer: Angiofibroma
Histology: The lesion consists of a densely fibrous mass situated beneath the surface squamous mucosa. Fibroblastic cells have a stellate appearance with enlarged nuclei revealing occasional nucleoli and minimal pleomorphism. The lesion is highly vascular with normal appearing endothelial cells line the vascular channels.
Discussion: Hemangiomas lack a densely fibrotic component and fibromas do not have a vascular element. Nasal polyps are composed of loose myxoid stroma and mucous glands covered by respiratory epithelium. They often contain prominent inflammation. Nasal polyps are not neoplasms but rather a polypoid reaction to inflammation and associated edema.
Incorrect
Answer: Angiofibroma
Histology: The lesion consists of a densely fibrous mass situated beneath the surface squamous mucosa. Fibroblastic cells have a stellate appearance with enlarged nuclei revealing occasional nucleoli and minimal pleomorphism. The lesion is highly vascular with normal appearing endothelial cells line the vascular channels.
Discussion: Hemangiomas lack a densely fibrotic component and fibromas do not have a vascular element. Nasal polyps are composed of loose myxoid stroma and mucous glands covered by respiratory epithelium. They often contain prominent inflammation. Nasal polyps are not neoplasms but rather a polypoid reaction to inflammation and associated edema.
