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Presented by Ralph Hruban, M.D. and prepared by Whitney Green, M.D.
Case 4: This 80-something year old underwent a pneunonectomy for carcinoma.
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Week 570: Case 4
This 80-something year old underwent a pneunonectomy for carcinoma. A separate incidental lesion was found.images/Case4_lowpower.jpg
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Answer: Pulmonary meningothelial-like nodule
Histology: This stellate nodule is composed of uniform, slightly spindle shaped cells in the interstitium. The nuclei are uniform.
Discussion: Pulmonary meningiothelial-like nodules are not uncommon incidental findings in the lung (10% of resections from men, 5% of resections from women). By electron microscopy and by immunolabeling they have meningeal differentiation.
Reference(s):
– Mizutani et al, Human Pathology, 2009; 40:678-82.Incorrect
Answer: Pulmonary meningothelial-like nodule
Histology: This stellate nodule is composed of uniform, slightly spindle shaped cells in the interstitium. The nuclei are uniform.
Discussion: Pulmonary meningiothelial-like nodules are not uncommon incidental findings in the lung (10% of resections from men, 5% of resections from women). By electron microscopy and by immunolabeling they have meningeal differentiation.
Reference(s):
– Mizutani et al, Human Pathology, 2009; 40:678-82.