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Presented by Hind Nassar, M.D. and prepared by Shiyama Mudali, M.D.
Case 3: Total thyroidectomy in a 23 y old woman with a current history of hyperthyroidism.
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1. Question
Week 450: Case 3
Total thyroidectomy in a 23 y old woman with a current history of hyperthyroidism and a previous history of hypothyroidism (at the age of 14).images/1alex/09132010case3image1.jpg
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images/1alex/09132010case3image5.jpgCorrect
Answer: Diffuse hyperplasia
Histology:
Discussion: Given the clinical history and the morphology, the process is diagnosed as diffuse hyperplasia (possibly due to Grave’s disease). In the hyperplastic areas there is papillary formation and some nuclear clearing, however the nuclear features characteristic of papillary thyroid carcinoma are absent.
Incorrect
Answer: Diffuse hyperplasia
Histology:
Discussion: Given the clinical history and the morphology, the process is diagnosed as diffuse hyperplasia (possibly due to Grave’s disease). In the hyperplastic areas there is papillary formation and some nuclear clearing, however the nuclear features characteristic of papillary thyroid carcinoma are absent.
