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Presented by Hind Nassar, M.D. and prepared by Aatur Singhi, M.D., Ph.D.
Case 3: 49 year old woman with an excisional biopsy for microcalcifications.
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1. Question
Week 424: Case 3
49 year old woman with an excisional biopsy for microcalcifications.images/1Alex/02072010case3image1.jpg
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images/1Alex/02072010case3image4.jpgCorrect
Answer: Ductal carcinoma in situ, low grade
Histology: none provided
Discussion: The intraductal proliferation is formed by monotonous cells partially or entirely involving ducts with extension into lobules. The cells are positive for E-Cadherin by immunostain. Since the lesion measures 5.0 mm in maximum dimension, it is best classified as low grade DCIS.
Incorrect
Answer: Ductal carcinoma in situ, low grade
Histology: none provided
Discussion: The intraductal proliferation is formed by monotonous cells partially or entirely involving ducts with extension into lobules. The cells are positive for E-Cadherin by immunostain. Since the lesion measures 5.0 mm in maximum dimension, it is best classified as low grade DCIS.