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Presented by Peter Illei, M.D. and prepared by Wang (Steve) Cheung, M.D., Ph.D.
Case 4: 91-year-old female with a history of squamous cell carcinoma to the anterior left leg.
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1. Question
Week 339: Case 4
91-year-old female with a history of squamous cell carcinoma to the anterior left leg. Wide excision of the prior biopsy site.images/205084a.jpg
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images/205084e.jpgCorrect
Answer: Basal cell carcinoma with separate in situ squamous cell carcinoma and actinic keratosis
Histology: Sections of this wide excision show marked solar damage including proliferative actinic keratosis with focal areas of marked dysplasia/in situ carcinoma. The infiltrating tumor in the center of the excision is a superficial basal cell carcinoma. The presence of clefting and apoptotic cells are more consistent with basal cell carcinoma rather than trichoepithelioma. No invasive squamous cell carcinoma is identified.
Discussion: none provided
Incorrect
Answer: Basal cell carcinoma with separate in situ squamous cell carcinoma and actinic keratosis
Histology: Sections of this wide excision show marked solar damage including proliferative actinic keratosis with focal areas of marked dysplasia/in situ carcinoma. The infiltrating tumor in the center of the excision is a superficial basal cell carcinoma. The presence of clefting and apoptotic cells are more consistent with basal cell carcinoma rather than trichoepithelioma. No invasive squamous cell carcinoma is identified.
Discussion: none provided
