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Presented by Ralph Hruban, M.D. and prepared by Natasha Rekhtman, M.D., Ph.D.
Case 5: This elderly patient with a history of a meningioma presented with a pleural mass.
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1. Question
Week 230: Case 5
This elderly patient with a history of a meningioma presented with a pleural mass.images/07 11 05 case 5 1.jpg
images/07 11 05 case 5 2.jpg
images/07 11 05 case 5 3.jpg
images/07 11 05 case 5 4.jpgCorrect
Answer: Meningioma metastatic to the pleura
Histology: This spindle cell neoplasm is remarkable for a syncytical growth pattern and focal “whorls.”
Discussion: The vast majority of meningiomas are entirely benign. Only 0.1% metastasize. They tend to be EMA positive. Other entities to consider in this case include the solitary fibrous tumor (SFT). SFTs usually express CD34 and bc12.
Incorrect
Answer: Meningioma metastatic to the pleura
Histology: This spindle cell neoplasm is remarkable for a syncytical growth pattern and focal “whorls.”
Discussion: The vast majority of meningiomas are entirely benign. Only 0.1% metastasize. They tend to be EMA positive. Other entities to consider in this case include the solitary fibrous tumor (SFT). SFTs usually express CD34 and bc12.
