Therapeutic Apheresis Program

AboutMake an AppointmentPrepare for Your AppointmentLocation, Hours & Parking

About the Therapeutic Apheresis Program

Patients are accepted by physician referral only.

The HATS Therapeutic Apheresis program supports a number of highly active clinical services and programs at Johns Hopkins Hospital, including Hematology/Oncology, Neurology, BMT Program, Solid Organ Transplantation and approved Clinical Research Studies.

Our program is staffed with skilled apheresis physicians and nurses committed to providing the highest quality patient care. Quality Assurance programs have been implemented to ensure compliance with regulatory and accreditation requirements, including those of the US Food and Drug Administration, the Maryland Department of Health and Mental Hygiene, The Joint Commission, the College of American Pathologist (CAP) and the Foundation of the Accreditation of Cellular Therapy (FACT).

The Therapeutic Apheresis Program performs the following services for patients seeking supportive treatment for many chronic or acute disorders requiring short- or long-term apheresis

  • LDL-Apheresis
  • Therapeutic Plasma Exchange
  • Plasmapheresis
  • Red Cell Exchange
  • Platelet Depletion
  • WBC Depletion
  • Hematopoietic stem cells collection (HPC)
  • T-cell collection


What is Apheresis?

Hemapheresis, (also called Apheresis), is a procedure used in the treatment of a variety of illnesses by which blood is removed from the body and separated into its 4 components: plasma, platelets, white blood cells, and red blood cells. The targeted blood component is then removed and the remaining blood cells, with or without a replacement fluid, are returned to the patient. This removal and replacing of the blood is done simultaneously to maintain proper fluid balance.



Most procedures are performed on an outpatient basis, during normal business hours. However, we have a team of apheresis physicians and nurses on call at any time for patients with urgent medical needs, and can provide apheresis treatment in any location in the hospital.

For more information, please refer to our HATS Apheresis Patient Education Brochure.

Our mission is to provide excellent quality healthcare to all patients in a safe, compassionate manner. We work closely with physicians to provide the therapy selected for your care.

Make an Appointment

Phone Number: 1-410-955-1717
For Billing questions: 1-410-955-6347


Patient Referral: If you are Physician looking to refer a patient to the Therapeutic Apheresis Program, call the phone number listed or page the HATS Attending on-call.


Prepare for Your Appointment

First-Time Patients Should Bring:
  • A complete list of your medications including the drug names, dosages, and times you take them
  • Insurance information
  • Photo Identification


What to Expect

Patients can expect a quiet, intimate atmosphere with personal attention from our dedicated apheresis nursing staff. We have fully reclining spacious chairs as well as televisions for your entertainment. Cold beverages are available and you may bring food to enjoy during your stay.

Patients are advised to dress comfortably and eat and drink before procedures.


  • Please call at least 24 hours in advance to cancel an appointment.
  • Please arrive 15 minutes prior to your appointment time. Allow extra time for traffic and parking.
  • If you are more than 15 minutes late for your appointment, we reserve the right to cancel your appointment. All efforts will be made to try to accommodate you, but understand you may need to reschedule your appointment.



Location, Hours of Operation & Parking

The Therapeutic Apheresis Program is located in the newly renovated Park Building.


Park Building 1st Floor
1800 Orleans Street
Baltimore, MD 21287
Johns Hopkins Hospital Directions & Parking


Hours of Operation

Monday – Friday 7:00am to 3:30pm.



Orleans Parking Garage
Location: Orleans Street, between North Broadway and North Wolfe
Entrances: Orleans Street or Fayette Street.

Caroline Street Garage
Location: Off of North Caroline Street, between McElderry and Monument.
Entrances: McElderry Street or East Monument Street.

Johns Hopkins Hospital Patient & Visitor Parking