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Presented by Dr. Matoso and prepared by Dr. Sintawat Wangsiricharoen.
A 74-year-old woman with end-stage renal disease and a renal tumor.
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1. Question
A 74-year-old woman with end-stage renal disease and a renal tumor.
Correct
Correct: D
Histology: This tumor is located within a cysts and is composed by tumor cells with abundant eosinophilic cytoplasm with cytoplasmic vacuoles or sieve spaces and multiple intracellular and extracellular calcium oxalate crystals. The background kidney shows signs of end-stage renal disease.
Discussion: As the name indicates, this tumor is found in patients with acquired cystic renal disease. They are usually small and often siagnosed in nephrectomy specimens for multicystic disease. They can be multiple and bilateral. Because they arise in a multicystic kidney, the tumor is often intracystic. The presence of sieve like spaces and calcium oxalate crystals are characteristic. They are usually indolent and most patients are cured with excision although they can develop a new lesion in the remaining kidney. These tumors are not graded.
References
Am J Surg Pathol. 2018 Sep;42(9):1156-1165.
Int J Urol. 2018 Sep;25(9):780-786.
Am J Surg Pathol. 2018 Oct;42(10):1396-1401.Incorrect
Correct: D
Histology: This tumor is located within a cysts and is composed by tumor cells with abundant eosinophilic cytoplasm with cytoplasmic vacuoles or sieve spaces and multiple intracellular and extracellular calcium oxalate crystals. The background kidney shows signs of end-stage renal disease.
Discussion: As the name indicates, this tumor is found in patients with acquired cystic renal disease. They are usually small and often siagnosed in nephrectomy specimens for multicystic disease. They can be multiple and bilateral. Because they arise in a multicystic kidney, the tumor is often intracystic. The presence of sieve like spaces and calcium oxalate crystals are characteristic. They are usually indolent and most patients are cured with excision although they can develop a new lesion in the remaining kidney. These tumors are not graded.
References
Am J Surg Pathol. 2018 Sep;42(9):1156-1165.
Int J Urol. 2018 Sep;25(9):780-786.
Am J Surg Pathol. 2018 Oct;42(10):1396-1401.
