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Presented by Hind Nassar, M.D. and prepared by Alex Chang, M.D.
Case 1: 30 year old male with a left index finger mass.
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Question 1 of 1
1. Question
Week 406: Case 1
30 year old male with a left index finger massimages/1alex/08312009case1image1.jpg
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images/1alex/08312009case1image4.jpgCorrect
Answer: Papillary endothelial hperplasia
Histology: none provided
Discussion: Intravascular papillary endothelial hyperplasia, first described by Masson as a neoplasm, is now considered an exuberant form of an organizing thrombus. Usually there is no history of trauma associated with it; therefore a biopsy is required to determine the nature of the lesion. Papillary endothelial hyperplasia can also occur in a background of a hemangioma, pyogenic granuloma or a vascular malformation. The differential diagnosis includes angiosarcoma; the latter is not usually confined to a vascular space as is the case for papillary endothelial hyperplasia. This lesion also lacks the atypia, mitoses, and necrosis that are seen in angiosarcoma.
Incorrect
Answer: Papillary endothelial hperplasia
Histology: none provided
Discussion: Intravascular papillary endothelial hyperplasia, first described by Masson as a neoplasm, is now considered an exuberant form of an organizing thrombus. Usually there is no history of trauma associated with it; therefore a biopsy is required to determine the nature of the lesion. Papillary endothelial hyperplasia can also occur in a background of a hemangioma, pyogenic granuloma or a vascular malformation. The differential diagnosis includes angiosarcoma; the latter is not usually confined to a vascular space as is the case for papillary endothelial hyperplasia. This lesion also lacks the atypia, mitoses, and necrosis that are seen in angiosarcoma.