Quiz-summary
0 of 1 questions completed
Questions:
- 1
Information
Presented by Pedram Argani, M.D. and prepared by Alex Chang, M.D.
Case 2: 43 year-old female with a 7 cm adrenal mass.
You have already completed the quiz before. Hence you can not start it again.
Quiz is loading...
You must sign in or sign up to start the quiz.
You have to finish following quiz, to start this quiz:
Results
Time has elapsed
Categories
- Not categorized 0%
- 1
- Answered
- Review
-
Question 1 of 1
1. Question
Week 403: Case 2
43 year-old female with a 7 cm adrenal mass.images/1alex/08102009case2image1.jpg
images/1alex/08102009case2image2.jpg
images/1alex/08102009case2image5.jpg
images/1alex/08102009case2image4.jpgCorrect
Answer: Myelolipoma
Histology: Within the adrenal there is a highly cellular proliferation of normal hematopoetic elements associated with fat. One sees megakaryocytes, a spectrum of maturing granulocytes, and islands of erythroid precursors. These are the typical features of a myelolipoma.
Discussion: Granulocytic sarcoma would feature sheets of primitive granulocytic cell precursors. Diffuse large B-cell lymphoma would feature sheets of pleomorphic lymphocytes with irregular nuclear contours and prominent nucleoli. Adrenal cortical carcinoma would demonstrate more polygonal cells with eosinophilic cytoplasm, reminiscent of the cytology of the normal adrenal cortex. Adrenal cortical carcinoma demonstrates cytologic atypia, and characteristically shows vascular and capsular invasion. Myelolipomas which are fat-poor, like the current case, are often difficult to distinguish from other adrenal lesions by imaging.
Incorrect
Answer: Myelolipoma
Histology: Within the adrenal there is a highly cellular proliferation of normal hematopoetic elements associated with fat. One sees megakaryocytes, a spectrum of maturing granulocytes, and islands of erythroid precursors. These are the typical features of a myelolipoma.
Discussion: Granulocytic sarcoma would feature sheets of primitive granulocytic cell precursors. Diffuse large B-cell lymphoma would feature sheets of pleomorphic lymphocytes with irregular nuclear contours and prominent nucleoli. Adrenal cortical carcinoma would demonstrate more polygonal cells with eosinophilic cytoplasm, reminiscent of the cytology of the normal adrenal cortex. Adrenal cortical carcinoma demonstrates cytologic atypia, and characteristically shows vascular and capsular invasion. Myelolipomas which are fat-poor, like the current case, are often difficult to distinguish from other adrenal lesions by imaging.