Answer: Peutz-Jeghers polyp

Histology: none provided

Discussion: Peutz-Jeghers polyps are the most common Hamartomatous polyps of the small intestine. They are composed of an admixture of epithelial elements and smooth muscle fibers that arise from an abnormally thickened muscularis mucosa. The epithelial cells are composed of intestinal absorptive cells, goblet cells, endocrine cells and Paneth cells. Recurrent acute abdominal pain secondary to intussusceptions is the most frequent complaint associated with this polyp. It is in general associated with Peutz-Jeghers syndrome (Hamartomatous polyps, mucocutaneous pigmentation, tumors of the ovary and testis). In this case patients with a polyp are at an increased risk for the development of dysplasia and carcinoma in the polyp and in the adjacent mucosa.