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Presented by Pedram Argani, M.D. and prepared by Amy Duffield, M.D., Ph.D.
Case 6: 8 year old male with an ear lesion.
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Question 1 of 1
1. Question
Week 336: Case 6
8 year old male with an ear lesion.images/1_21_08 6A.jpg
images/1_21_08 6B.jpg
images/1_21_08 6C.jpg
images/1_21_08 6D.jpg
images/1_21_08 6E.jpgCorrect
Answer: Calcinosis Cutis
Histology: This lesion consists of dense calcification involving the dermis underlying a hyperplastic epidermis. No atypical cells are seen.
Discussion: Chondrosarcoma and osteosarcoma would be characterized by malignant mesenchymal cells, which produce cartilage or bone. The current material would stain with the von Kassa stain, proving that it is calcium.
Cutaneous calcification may be divided into dystrophic calcification, which is associated with connective tissue injury and not serum hypercalcemia, and metastatic calcification, which is associated with serum hypercalcemia. Selective calcification of vessel walls suggest metastatic calcification associated with hypercalcemia. Calcinosis cutis generally refers to the dystrophic type of calcification. This may be idiopathic (often familial), associated with fat necrosis, associated with dermatomyositis or other connective tissue disease, or associated with diabetes.
Incorrect
Answer: Calcinosis Cutis
Histology: This lesion consists of dense calcification involving the dermis underlying a hyperplastic epidermis. No atypical cells are seen.
Discussion: Chondrosarcoma and osteosarcoma would be characterized by malignant mesenchymal cells, which produce cartilage or bone. The current material would stain with the von Kassa stain, proving that it is calcium.
Cutaneous calcification may be divided into dystrophic calcification, which is associated with connective tissue injury and not serum hypercalcemia, and metastatic calcification, which is associated with serum hypercalcemia. Selective calcification of vessel walls suggest metastatic calcification associated with hypercalcemia. Calcinosis cutis generally refers to the dystrophic type of calcification. This may be idiopathic (often familial), associated with fat necrosis, associated with dermatomyositis or other connective tissue disease, or associated with diabetes.
