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Presented by Ralph Hruban, M.D. and prepared by Natasha Rekhtman, M.D., Ph.D.
Case 6: This elderly male with a history of treated squamous cell carcinoma underwent a neck dissection.
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1. Question
Week 230: Case 6
This elderly male with a history of treated squamous cell carcinoma underwent a neck dissection./images/07 11 05 case 6 1.jpg
/images/07 11 05 case 6 2.jpg
/images/07 11 05 case 6 3.jpgCorrect
Answer: Acellular keratin granuloma
Histology: One of the lymph nodes contains acellular keratinous debris with an associated foreign-body type giant cell reaction. No viable tumor cells are seen.
Discussion: This acellular keratinous debris represents treated tumor. The important message to communicate to the clinicians is that while the keratin indicates that there once was tumor in this node, it is no longer viable.
Incorrect
Answer: Acellular keratin granuloma
Histology: One of the lymph nodes contains acellular keratinous debris with an associated foreign-body type giant cell reaction. No viable tumor cells are seen.
Discussion: This acellular keratinous debris represents treated tumor. The important message to communicate to the clinicians is that while the keratin indicates that there once was tumor in this node, it is no longer viable.
