Dr. Joseph Herman

Joseph Herman, M.D., M.Sc.

Dr. Herman can be contacted at the following address:Dr. Joseph Herman

Johns Hopkins Hospital
The Harry and Jeanette Weinberg Building
Suite 1440
401 North Broadway
Baltimore, MD 21231

Appointments: 410-955-8964
Email: jherma15@jhmi.edu
Phone: (410) 502-3823
Fax: (410) 502-1419
Website: www.radonc.jhmi.edu

RESEARCH ACTIVITIES
Publications

1) Tayebi N, Herman J, et al. Different recombinational events between the GC gene and pseudogene in patients with type 1, 2, and 3 Gaucher disease. A J Hum Genet. 57(4):1329, 1995.

2) Sidransky E, Tayebi N, Herman J, et al. Genotypic and phenotypic heterogeneity in type 2 Gaucher disease. Am J Hum Genet. 57(4):1453, 1995.

3) Tayebi N, Stern H, Dymarskaia I, Herman J, et al. 55 Base pair deletion in certain patients with Gaucher disease complicates screening for Gaucher alleles. Am J Med Genet. 66:316-319, 1996.

4) Tayebi N, Herman J, et al. Genotype D399/R463C in a patient with type 3 Gaucher disease previously assigned genotype N370/R463C. Biochem Mol Med. 57:149-151, 1996.

5) Solomon G, Huddle A, Silbergeld E, Herman J. Manganese in Gasoline: Are we repeating history? New Solutions. Winter:17-24, 1997.

6) Edelman D, Ketema F, Saville R, Herman J, Blattner W, et al. Specifics on the refinement and application of two serological assays for the detection of antibodies to HHV-8. J. Clinical Virology. 16(3):225-237, 2000.

7) Suntharalingam, MH, Conley ML, Egorin BA, Levy MH, Sivasailam S, Herman JM, et al. The use of carboplatin and paclitaxel with daily radiotherapy in patients with locally advanced squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys. 47(1):49-56, 2000.

8) Nwokedi EC, DiBiase SJ, Jabbour S, Herman J, et al. Gamma knife stereotactic radiosurgery for patients with glioblastoma multiforme. Neurosurgery. 50(1):41-46, 2002.

9) Petit J, Herman J, et al. Radiosurgical treatment of trigeminal neuralgia: evaluating quality of life and treatment outcomes. Int J Radiat Oncol Biol Phys. 56(4):1147-1153, 2003.

10) Herman J, Smith D, Sandler H, et al. Quality of Life (QOL) assessment in patients receiving concurrent Gemcitabine and radiotherapy as a bladder preservation strategy. Urology. Jul 64(1):69-73, 2004.

11) Herman J, Petit J, et al. Repeat Gamma Knife Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia: Treatment Outcomes and Quality of Life Assessment. Int J Rad Oncol Biol Phys. 59(1):112-116, 2004.

12) Kent E, Montie J, Lee C, Sandler H, Herman J, et al. Combined-modality therapy with Gemcitabine and radiotherapy as a bladder preservation strategy: results of a phase I trial. J Clin Oncol. Jul 22(13):2540-2545, 2004.

13) Cheuk A, Chin L, Petit J, Herman J, et al. Imaging correlates of gamma knife outcome in trigeminal neuralgia. Int J Rad Oncol Biol Phys. 60(2):537-541, 2004.

14) Alexander B, Wechsler D, Braun T, Levine J, Herman J, Yanik G, Hutchinson R, Pierce L. Utility of Cranial Boost in Addition to Total Body Irradiation in the Treatment of High Risk Acute Lymphoblastic Leukemia. Int J Rad Oncol Biol Phys. 63(4):1191-1196, 2005.

15) McLaughlin P, Narayana V, Pan C, Berri S, Troyer S, Herman J, et al. Comparison of day 0 and day 14 dosimetry for permanent prostate implants using stranded seeds. Int J Rad Oncol Biol Phys. 64(1):144-150, 2006.

16) McHugh J, Thomas D, Herman J, Ray M, Baker L, Volkan Adsay N, Rabah R, Lucas D. Primary versus Radiation-Associated Craniofacial Osteosarcoma: Biological and Clinicopathologic Comparisons. Cancer. 107:554-562, 2006.

17) Assumpcao L, Choti MA, Gleisner AL, Schulick RD, Swartz M, Herman J, Gearhart SL, Pawlik TM. Patterns of Recurrence following Liver Resection for Colorectal Metastases: Impact of Primary Rectal Tumor Site. Arch Surg. 2008 Aug;143(8):743-9; discussion 749-50.

18) Swartz M, Hughes M, Frassica D, Herman J, Yeo C, et al. Adjuvant concurrent chemoradiation for node-positive adenocarcinoma of the duodenum. Arch Surg. 142(3):285-288, 2007.

19) Rodriguez-Paz J, Mark L, Herzer KR, Michelson JD, Grogan KLl, Herman J, Hunt D, Wardlow L, Armour E, Pronovost PJ. Using In-Situ Simulation to Establish a New Intraoperative Radiation Therapy Program: A Novel Disciplinary Paradigm to Patient Safety. Accepted to Anesthesia and Analgesia, 4/08.

20) Karikari C, Roy I, Tryggestad E, Feldmann G, Pinilla C, Reed J, Armour E, Wong J, Herman J, Rakheja D, Maitra A. Targeting the Apoptotic Machinery in Pancreatic Cancers using Small Molecule Antagonists of the X-linked Inhibitor of Apoptosis (XIAP) Protein. Mol Cancer Ther. 6(3):957-966, 2007.

21) Pawlik TM, Ahuja N, Herman JM. The Role of Radiation in Retroperitoneal Sarcomas: A Surgical Perspective. Curr Opin Oncol. 19(4):359-366, 2007.

22) Lopez CA, Feng FF, Herman JM, Nyati M, Lawrence TS, Ljungman M. Phenylbutyrate Sensitize Human Glioblastoma Cells Lacking Wild Type p53 Function to Ionizing Radiation. Int J Rad Onc Biol Phys. 69(1):214-220, 2007.

23) Poggi MM, Suh WW, Saltz L, Konski AA, Mohiuddin M, Herman J, Johnstone PA. ACR Appropriateness Criteria on treatment of anal cancer. J Am Coll Radiol. Jul;4(7):448-56, 2007.

24) Gleisner AL, Assumpcao L, Cameron JL, Wolfgang CL, Choti MA, Herman JM, Schulick RD, Pawlik TM. Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified? Cancer. Dec 1;110(11):2484-92, 2007.

25) Herman JM, Messersmith WA, Johnstone PA, Blackstock AW, Konski AA, Mohiuddin M, Poggi MM, Regine WF, Rich TA, Suh WW, Cosman BC, Saltz L. Expert Panel on Radiation Oncology-Rectal/Anal Cancer Work Group: Rectal Cancer-Metastatic Disease at Presentation. ACR Website Treatment Criteria 9/07.

26) Konski AA, Herman JM, Johnstone PA, Blackstock AW, Mohiuddin A, Poggi, MM, Regine WF, Rich TA, Suh WW, Cosman BC, Saltz L. Expert Panel on Radiation Oncology-Rectal/Anal Work Group: Recurrent Rectal Cancer. ACR Website Treatment Criteria 3/08.

27) Suh WW, Johnstone PA, Herman J, Blackstock AW, Konski AA, Mohiuddin M, Poggi MM, Regine WF, Rich TA, Cosman BC, Saltz L. Expert Panel on Radiation Oncology-Rectal/Anal Cancer Panel: Resectable Rectal Cancer. Int J Radiat Oncol Biol Phys. Apr 1;70(5):1427-30, 2008.

28) Hruban RH, Maitra A, Schulick R, Laheru D, Herman J, Kern SE, Goggins M. Emerging Molecular Biology of Pancreatic Cancer. Gastrointest Cancer Research 2008 (supp 2) S11-S16.

29) Slidell MB, Gleisner AL, Cameron JL, Chang DC, Wolfgang C, Herman JM, Schulick RD, Choti MA, Pawlik TM. Impact of Total Lymph Node Count and Lymph Node Ratio on Staging and Survival after Pancreatectomy for Pancreatic Adenocarcinoma: A Large, Population-Based Analysis. Ann Surg Oncol. Jan;15(1):165-74, 2008

30) Herman JM, Swartz MJ, Hsu CC, Winter J, Pawlik TM, Sugar E, Robinson R, Laheru D, Jaffee E, Hruban R, Campbell K, Wolfgang C, Donehower R, Hidalgo M, Diaz Jr., L , Frassica D, Yeo C, Cameron J, Schulick R, Abrams R. Analysis of Adjuvant Chemotherapy and Radiation after Pancreaticoduodenectomy for Ductal Adenocarcinoma of the Pancreas: Results of a Large Prospectively Collected Database. J Clin Oncol. 2008 Jul 20;26(21):3503-10.

31) Herman J, Sandler H, Hiniker S, Pierce L. Radiotherapy Using a Water Bath in the Treatment of Bowen’s Disease of the Digit. Accepted with revisions, Radiotherapy and Oncology. Radiother Oncol. 2008 Jun 19. [Epub ahead of print]

32) Pawlik TM, Laheru D, Hruban R, Voong R, Coleman J, Wolfgang, Raben M, Edil B, Asrari F, Campbell K, Makary M, Ali S, Donehower R, Diaz L, Fishman E, Schulick R, Herman JM. Evaluating the Impact of a Single Day Multidisciplinary Clinic on the Management of Pancreatic Cancer. Ann Surg Oncol. 2008 Aug;15(8):2081-8. Epub 2008 May 7

33) Reddy S, Edil B, Cameron J, Pawlik TM, Herman JM, Gilson M, Campbell K, Schulick R, Ahuja N, Wolfgang C. Resection of Metastatic Cancer to the Pancreas: A Retrospective Analysis of Safety and Efficacy. Ann Surg Oncol. 2008 Sep 11. [Epub ahead of print]

34) Iacobuzio-Donahue CA, Fu B, Yachida S, Luo M, Abe H, Henderson CM, Vilardell F, Wang Z, Keller J, Lakkur S, Banerjee P, Herman JM, Cameron JL, Yeo CJ, Halushka MK, Eshleman JR, Raben Klein AP, Hruban RH, Hidalgo M, Laheru D. DPC4 Gene Status of the Primary Carcinoma Correlates with Local versus Metastatic Failure in Patients with Pancreatic Cancer: Observations from the Gastrointestinal Cancer Rapid Medical Donation Program. Accepted to JCO 7/08.

35) Hueman MT, Herman JM, Ahuja N. Management of Retroperitoneal Sarcomas. Surg Clin North Am. 2008 Jun;88(3):583-97, vii.

36) Hueman MT, Thornton K, Herman JM, Ahuja N Management of extremity soft tissue sarcomas. Surg Clin North Am. 2008 Jun;88(3):539-57, vi

37) Rodriguez-Paz JM, Mark L, Herzer K, Michelson J, Grogan K, Herman J, Hunt D, Wardlow L, Armour E, Pronovost P. A Novel Process for Introducing a New Intraoperative Program: A Multidisciplinary Paradigm for Mitigating Hazards and Improving Patient Safety. Anesth Analg. Accepted 8/2008.

38) Herzer K, Rodriguez-Paz J, Doyle P, Flint P, Feller-Kopman D, Herman J, Bristow R, Cover R, Pronovost P, Mark L. A Practical Framework for Patient Care Teams to Prospectively Identify and Mitigate Clinical Hazards. Jt Comm J Qual Patient Saf. Accepted 8/2008.

39) Assumpcao L, Cameron JL, Wolfgang CL, Edil B, Choti M, Herman JM, Geschwind J, Hong K, Georgiades C, Schulick RD, Pawlik TM. Incidence and Management of Chyle Leaks following Pancreatic Resection: A High Volume Single-Center Institutional Experience. J Gastrointest Surg. 2008 Aug 7. [Epub ahead of print]

RECOGNITION
Awards, Honors

1994 Letter of Commendation, National Institutes of Health, Neurogenetics Section
1994 Selected Male Scholar/Athlete of the Year – Salisbury State University
1995 Graduate Merit Award, UMAB Master of Science in Preventive Medicine
1997 Awarded STRTP NIH grant to develop an IFA assay for HHV-8 and Kaposi’s Sarcoma
2000 Outstanding Student Achievement Award in Radiation Oncology and Pathology – University of Maryland
2001 Awarded Intern of the Month, University of Michigan Internal Medicine
2005 Chief Resident, University of Michigan Department of Radiation Oncology
2005 Awarded RSNA Resident of the Year (University of Michigan)
2006 Awarded stipend to participate in the 2006 AACR/ASCO Workshop on Methods in Clinical Cancer Research
2008 AACR Career Development Award for Pancreatic Cancer Research
2008 Johns Hopkins Teaching Award
2008 Junior Faculty Award to present at SANTRO (Ampullary Cancer)