Eberhart & Bar

1) JE. Kratz, D Stearns, DL Huso, HH Slunt, DL Price, DR Borchelt, CG Eberhart. Expression of stabilized beta-catenin in the CNS of adult transgenic mice does not result in tumor formation. BMC Cancer 2002, 2:33.

2) X Fan, Y Wang, J Kratz, DJ Brat, Y Robitaille, A Moghrabi, EJ Perlman, CV.  Dang, PC Burger, CG Eberhart. hTERT Gene Amplification and Increased mRNA Expression in CNS Embryonal Tumors. Am J Pathol 2003, 162(6):1763-9.

3) X Fan, I Mikolaenko, I Elhassan, XZ Ni, Y Wang, D Ball, DJ Brat, A Perry, and CG. Eberhart. Notch1 and Notch2 have opposite effects on embryonal brain tumor growth. Cancer Res. 2004, 64(21):7787-93

4) TW Abel, SJ Baker, MM Fraser, T Tihan, JS Nelson, A Yachnis, J Bouffard, H Mena, PC Burger, CG Eberhart. Lhermitte-Duclos Disease: a Report of 31 Cases with Immunohistochemical Analysis of the PTEN/AKT/mTOR Pathway. J Neuropath Exp Neurol. 2005, 64:1-9.

5) Dang L, Fan X, Chaudhry A, Wang M, Gaiano N, and CG Eberhart. Notch3 Signaling Initiates Choroid Plexus Tumor Formation. Oncogene 2006, 25:487-91.

6) D Stearns, A Chaudhry, T Abel, PC. Burger, CV. Dang, CG Eberhart. c-Myc Overexpression Causes Anaplasia in Medulloblastoma. Cancer Res. 2006, 66:673-81.

7) X Fan, W Matsui, L Khaki, D Stearns, J Chun, YM Li, CG Eberhart. Notch Pathway Blockade Selectively Depletes Stem-like Embryonal Brain Tumor Cells. Cancer Research 2006 66:7445-52.

8) E Bar, A Chaudhry, CG Eberhart. Hedgehog Signaling Promotes Medulloblastoma Survival via Bcl2. American Journal of Pathology 2007, 170:347-55.

9) Bar EE, Chaudhry A, Lin A, Fan X, Schreck K, Matsui W, Vescovi AL, Piccirillo S, Dimeco F, Olivi A, Eberhart CG. Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma. Stem Cells. 2007, 25:2524-33.

10) Bar EE, Lin A, Tihan T, Burger PC, Eberhart CG. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol. 2008, 67:878-87.

11) Fan X, Eberhart CG, Medulloblastoma stem cells. J Clin Oncol. 2008, 26:2821-7.

12) Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG. NOTCH Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts. Stem Cells. 2010, 28(1):5-16.

13) Bar EE, Lin A, Mahairaki V, Matsui W, and Eberhart CG. Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres. Am J Pathol 2010, 177(3):1491-502.

14) Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG.  The notch target hes1 directly modulates gli1 expression and hedgehog signaling:  a potential mechanism of therapeutic resistance.  Clin Cancer Res 2010:16(24):6060-70.

15) Eberhart CG.  Molecular diagnostics in embryonal brain tumors.  Brain Pathol 2011:21(1):96-104.

16) Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG.  A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors.  Cancer Biol Ther 2011

17) Bar EE. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol. 2011 Mar;21(2):119-29.